First, the best time to give your cats their medication, is the morning after a good night's sleep. I am more relaxed at the time and tend to get easier.
Giving medication to your pet is not like giving your kids.
The best way to get the cat to take medication is always kind.
If the drug in pill form, it is better to be broken down into real small pieces.
I have never used the method to force the pill down my cat's mouth, because you can not frustrate the cat.
I usually make my house cat and is very comfortable in my lap and talk quietly before giving her medicine in the food wet or dry.